Data harmonisation Design and creation of a unified clinical data scheme including conversion maps for all involved clinical partners. WP lead Joslin Diabetes Center (USA) → Sanjeev Mehta
WP2
Federated dAIbetes-Net Connect at least four isolated and globally distributed independent repositories with longitudinal data from type 2 diabetes patients. WP lead Institute for Computational Systems Biology University of Hamburg (DE) → Jan Baumbach
WP3
Federated virtual twin models Development of dAIbetes virtual twin apps for training of virtual twin models that will use data from type 2 diabetes patients. WP lead Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) → Bjoern Eskofier
WP4
dAIbetes software platform Design, architecture and development of the virtual twin software platform. WP lead egnosis (RO) → Béla Bihari
WP5
dAIbetes validation study Demonstrate the ability of the dAIbetes virtual twin models to forecast the impact of a given treatment for type 2 diabetes on a biomarker of interest. WP lead Brigham and Women's Hospital (US) → Elliott Antman
WP6
Legal and ethical assessment Development and application of a methodology, which meets the specifics of dAIbetes and the requirements of the current regulatory ethics and legal framework. WP lead Research Institute AG & Co KG (AT) → Walter Hötzendorfer
WP7
Project management Interdisciplinary project supervision and international networking. WP lead Institute for Computational Systems Biology University of Hamburg (DE) → Jan Baumbach
WP8
Dissemination and exploitation Inform the public, clinics, academia and stakeholders. Sustainable maintenance of the health data platform. WP lead tp21 GmbH (DE) → Petra Zalud
WP9
Ethics Ensure compliance with the relevant ethics requirements through an external ethics advisor. WP lead Institute for Computational Systems Biology University of Hamburg (DE) → Jan Baumbach